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Effects of Tenofovir on Cytokines and Nucleotidases in HIV-1 Target Cells and the Mucosal Tissue Environment in the Female Reproductive Tract

Tenofovir (TFV) is a reverse transcriptase inhibitor used in microbicide preexposure prophylaxis trials to prevent HIV infection. Recognizing that changes in cytokine/chemokine secretion and nucleotidase biological activity can influence female reproductive tract (FRT) immune protection against HIV...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Biswas, Nabanita, Rodriguez-Garcia, Marta, Shen, Zheng, Crist, Sarah G., Bodwell, Jack E., Fahey, John V., Wira, Charles R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249387/
https://ncbi.nlm.nih.gov/pubmed/25136003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.03270-14
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