Sex Hormones Regulate Tenofovir-Diphosphate in Female Reproductive Tract Cells in Culture

The conflicting results of recent pre-exposure prophylaxis (PrEP) trials utilizing tenofovir (TFV) to prevent HIV infection in women led us to evaluate the accumulation of intracellular TFV-diphosphate (TFV-DP) in cells from the female reproductive tract (FRT) and whether sex hormones influence the...

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Autori principali: Shen, Zheng, Fahey, John V., Bodwell, Jack E., Rodriguez-Garcia, Marta, Kashuba, Angela D. M., Wira, Charles R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4076265/
https://ncbi.nlm.nih.gov/pubmed/24978212
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0100863
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