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Tenofovir Inhibits Wound Healing of Epithelial Cells and Fibroblasts from the Upper and Lower Human Female Reproductive Tract

Disruption of the epithelium in the female reproductive tract (FRT) is hypothesized to increase HIV infection risk by interfering with barrier protection and facilitating HIV-target cell recruitment. Here we determined whether Tenofovir (TFV), used vaginally in HIV prevention trials, and Tenofovir a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Rodriguez-Garcia, Marta, Patel, Mickey V., Shen, Zheng, Bodwell, Jack, Rossoll, Richard M., Wira, Charles R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5377941/
https://ncbi.nlm.nih.gov/pubmed/28368028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45725
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