Antigen Reversal Identifies Targets of Opsonizing IgGs against Pregnancy-Associated Malaria

Clinical immunity to pregnancy associated-malaria (PAM) in multigravida women has been attributed to antibodies that recognize VAR2CSA on the infected erythrocyte (IE) surface. The size and complexity of VAR2CSA have focused efforts on selecting one or more of its six Duffy binding-like (DBL) domain...

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Dettagli Bibliografici
Pubblicato in:Infect Immun
Autori principali: Lambert, Lester H., Bullock, Jeanee L., Cook, Sharma T., Miura, Kazutoyo, Garboczi, David N., Diakite, Mahamadou, Fairhurst, Rick M., Singh, Kavita, Long, Carole A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
Soggetti:
Fungal and Parasitic Infections
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249335/
https://ncbi.nlm.nih.gov/pubmed/25156731
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02097-14
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