Cooperativity among Rev-Associated Nuclear Export Signals Regulates HIV-1 Gene Expression and Is a Determinant of Virus Species Tropism

Murine cells exhibit a profound block to HIV-1 virion production that was recently mapped to a species-specific structural attribute of the murine version of the chromosomal region maintenance 1 (mCRM1) nuclear export receptor and rescued by the expression of human CRM1 (hCRM1). In human cells, the...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Aligeti, Mounavya, Behrens, Ryan T., Pocock, Ginger M., Schindelin, Johannes, Dietz, Christian, Eliceiri, Kevin W., Swanson, Chad M., Malim, Michael H., Ahlquist, Paul, Sherer, Nathan M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2014
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249125/
https://ncbi.nlm.nih.gov/pubmed/25275125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01897-14
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