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Nuclear Export Signal Masking Regulates HIV-1 Rev Trafficking and Viral RNA Nuclear Export

HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functional fluorescently tagged Rev fusion prot...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Behrens, Ryan T., Aligeti, Mounavya, Pocock, Ginger M., Higgins, Christina A., Sherer, Nathan M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5244332/
https://ncbi.nlm.nih.gov/pubmed/27852860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02107-16
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