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Matrix Mediates the Functional Link between Human Immunodeficiency Virus Type 1 RNA Nuclear Export Elements and the Assembly Competency of Gag in Murine Cells

Human immunodeficiency virus type 1 (HIV-1) assembles poorly in murine cells, reflecting inefficient targeting of the Gag structural polyprotein to the plasma membrane. Virus particle production can be restored by replacing the cis-acting Rev response element (RRE) in Gag-Pol mRNAs with multiple cop...

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Hlavní autoři: Sherer, Nathan M., Swanson, Chad M., Papaioannou, Stelios, Malim, Michael H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2009
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2738188/
https://ncbi.nlm.nih.gov/pubmed/19535446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00699-09
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