Emergence of human immunodeficiency virus type 1 variants with resistance to multiple dideoxynucleosides in patients receiving therapy with dideoxynucleosides.

A set of mutations [Ala-62-->Val(A62V), V75I, F77L, F116Y, and Q151M] in the polymerase domain of reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) confers on the virus a reduced sensitivity to multiple antiretroviral dideoxynucleosides and has been seen in HIV-1 variants...

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Detalhes bibliográficos
Main Authors: Shirasaka, T, Kavlick, M F, Ueno, T, Gao, W Y, Kojima, E, Alcaide, M L, Chokekijchai, S, Roy, B M, Arnold, E, Yarchoan, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC42491/
https://ncbi.nlm.nih.gov/pubmed/7534421
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