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Circulating Clinical Strains of Human Parainfluenza Virus Reveal Viral Entry Requirements for In Vivo Infection

Human parainfluenza viruses (HPIVs) cause widespread respiratory infections, with no vaccines or effective treatments. We show that the molecular determinants for HPIV3 growth in vitro are fundamentally different from those required in vivo and that these differences impact inhibitor susceptibility....

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Palmer, Samantha G., DeVito, Ilaria, Jenkins, Stephen G., Niewiesk, Stefan, Porotto, Matteo, Moscona, Anne
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249073/
https://ncbi.nlm.nih.gov/pubmed/25210187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-14
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