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Circulating Clinical Strains of Human Parainfluenza Virus Reveal Viral Entry Requirements for In Vivo Infection

Human parainfluenza viruses (HPIVs) cause widespread respiratory infections, with no vaccines or effective treatments. We show that the molecular determinants for HPIV3 growth in vitro are fundamentally different from those required in vivo and that these differences impact inhibitor susceptibility....

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Palmer, Samantha G., DeVito, Ilaria, Jenkins, Stephen G., Niewiesk, Stefan, Porotto, Matteo, Moscona, Anne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249073/
https://ncbi.nlm.nih.gov/pubmed/25210187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-14
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