Circulating Clinical Strains of Human Parainfluenza Virus Reveal Viral Entry Requirements for In Vivo Infection

Human parainfluenza viruses (HPIVs) cause widespread respiratory infections, with no vaccines or effective treatments. We show that the molecular determinants for HPIV3 growth in vitro are fundamentally different from those required in vivo and that these differences impact inhibitor susceptibility....

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Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Palmer, Samantha G., DeVito, Ilaria, Jenkins, Stephen G., Niewiesk, Stefan, Porotto, Matteo, Moscona, Anne
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2014
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4249073/
https://ncbi.nlm.nih.gov/pubmed/25210187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01965-14
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