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Stepwise Priming by Acidic pH and a High K(+) Concentration Is Required for Efficient Uncoating of Influenza A Virus Cores after Penetration
Influenza A virus (IAV) uses the low pH in late endocytic vacuoles as a cue for penetration by membrane fusion. Here, we analyzed the prefusion reactions that prepare the core for uncoating after it has been delivered to the cytosol. We found that this priming process occurs in two steps that are me...
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| Publicado no: | J Virol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4249060/ https://ncbi.nlm.nih.gov/pubmed/25165113 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01430-14 |
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