Chargement en cours...
Exonuclease Domain of the Lassa Virus Nucleoprotein Is Critical To Avoid RIG-I Signaling and To Inhibit the Innate Immune Response
Lassa virus (LASV), which causes a viral hemorrhagic fever, inhibits the innate immune response. The exonuclease (ExoN) domain of its nucleoprotein (NP) is implicated in the suppression of retinoic acid-inducible gene I (RIG-I) signaling. We show here that a LASV in which ExoN function has been abol...
Enregistré dans:
| Publié dans: | J Virol |
|---|---|
| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2014
|
| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4248989/ https://ncbi.nlm.nih.gov/pubmed/25253344 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01923-14 |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|