Characterization of a Broadly Neutralizing Monoclonal Antibody That Targets the Fusion Domain of Group 2 Influenza A Virus Hemagglutinin

Due to continuous changes to its antigenic regions, influenza viruses can evade immune detection and cause a significant amount of morbidity and mortality around the world. Influenza vaccinations can protect against disease but must be annually reformulated to match the current circulating strains....

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Udgivet i:J Virol
Main Authors: Tan, Gene S., Lee, Peter S., Hoffman, Ryan M. B., Mazel-Sanchez, Beryl, Krammer, Florian, Leon, Paul E., Ward, Andrew B., Wilson, Ian A., Palese, Peter
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Vaccines and Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248980/
https://ncbi.nlm.nih.gov/pubmed/25210195
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02289-14
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