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M27 Expressed by Cytomegalovirus Counteracts Effective Type I Interferon Induction of Myeloid Cells but Not of Plasmacytoid Dendritic Cells

In healthy individuals, the functional immune system effectively confines human cytomegalovirus (CMV) replication, while viral immune evasion and persistence preclude sterile immunity. Mouse CMV (MCMV) is a well-established model to study the delicate CMV-host balance. Effective control of MCMV infe...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Döring, Marius, Lessin, Irina, Frenz, Theresa, Spanier, Julia, Kessler, Annett, Tegtmeyer, Pia, Dağ, Franziska, Thiel, Nadine, Trilling, Mirko, Lienenklaus, Stefan, Weiss, Siegfried, Scheu, Stefanie, Messerle, Martin, Cicin-Sain, Luka, Hengel, Hartmut, Kalinke, Ulrich
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248974/
https://ncbi.nlm.nih.gov/pubmed/25231302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00216-14
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