M27 Expressed by Cytomegalovirus Counteracts Effective Type I Interferon Induction of Myeloid Cells but Not of Plasmacytoid Dendritic Cells

In healthy individuals, the functional immune system effectively confines human cytomegalovirus (CMV) replication, while viral immune evasion and persistence preclude sterile immunity. Mouse CMV (MCMV) is a well-established model to study the delicate CMV-host balance. Effective control of MCMV infe...

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Vydáno v:J Virol
Hlavní autoři: Döring, Marius, Lessin, Irina, Frenz, Theresa, Spanier, Julia, Kessler, Annett, Tegtmeyer, Pia, Dağ, Franziska, Thiel, Nadine, Trilling, Mirko, Lienenklaus, Stefan, Weiss, Siegfried, Scheu, Stefanie, Messerle, Martin, Cicin-Sain, Luka, Hengel, Hartmut, Kalinke, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248974/
https://ncbi.nlm.nih.gov/pubmed/25231302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00216-14
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