Human monocyte-derived macrophages inhibit HCMV spread independent of classical antiviral cytokines

Infection of healthy individuals with human cytomegalovirus (HCMV) is usually unnoticed and results in life-long latency, whereas HCMV reactivation as well as infection of newborns or immunocompromised patients can cause life-threatening disease. To better understand HCMV pathogenesis we studied mec...

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Detalhes bibliográficos
Main Authors: Jennifer Becker, Volker Kinast, Marius Döring, Christoph Lipps, Veronica Duran, Julia Spanier, Pia-Katharina Tegtmeyer, Dagmar Wirth, Luka Cicin-Sain, Antonio Alcamí, Ulrich Kalinke
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis Group 2018-12-01
Colecção:Virulence
Assuntos:
Human cytomegalovirus
macrophages
plasmacytoid dendritic cells
type I interferons
epithelial cells
Acesso em linha:http://dx.doi.org/10.1080/21505594.2018.1535785
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