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trans-Protease Activity and Structural Insights into the Active Form of the Alphavirus Capsid Protease

The alphavirus capsid protein (CP) is a serine protease that possesses cis-proteolytic activity essential for its release from the nascent structural polyprotein. The released CP further participates in viral genome encapsidation and nucleocapsid core formation, followed by its attachment to glycopr...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Aggarwal, Megha, Dhindwal, Sonali, Kumar, Pravindra, Kuhn, Richard J., Tomar, Shailly
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248945/
https://ncbi.nlm.nih.gov/pubmed/25100849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01692-14
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