Cross-Clade Ultrasensitive PCR-Based Assays To Measure HIV Persistence in Large-Cohort Studies

A small pool of infected cells persists in HIV-infected individuals receiving antiretroviral therapy (ART). Here, we developed ultrasensitive assays to precisely measure the frequency of cells harboring total HIV DNA, integrated HIV DNA, and two long terminal repeat (2-LTR) circles. These assays are...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Vandergeeten, Claire, Fromentin, Rémi, Merlini, Esther, Lawani, Mariam B., DaFonseca, Sandrina, Bakeman, Wendy, McNulty, Amanda, Ramgopal, Moti, Michael, Nelson, Kim, Jerome H., Ananworanich, Jintanat, Chomont, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248919/
https://ncbi.nlm.nih.gov/pubmed/25122785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00609-14
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