Modulation of Hepatitis C Virus Genome Replication by Glycosphingolipids and Four-Phosphate Adaptor Protein 2

Hepatitis C virus (HCV) assembles its replication complex on cytosolic membrane vesicles often clustered in a membranous web (MW). During infection, HCV NS5A protein activates PI4KIIIα enzyme, causing massive production and redistribution of phosphatidylinositol 4-phosphate (PI4P) lipid to the repli...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Khan, Irfan, Katikaneni, Divya S., Han, Qingxia, Sanchez-Felipe, Lorena, Hanada, Kentaro, Ambrose, Rebecca L., Mackenzie, Jason M., Konan, Kouacou V.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2014
Sujets:
Genome Replication and Regulation of Viral Gene Expression
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248901/
https://ncbi.nlm.nih.gov/pubmed/25122779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00970-14
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