Modulation of Hepatitis C Virus Genome Replication by Glycosphingolipids and Four-Phosphate Adaptor Protein 2

Hepatitis C virus (HCV) assembles its replication complex on cytosolic membrane vesicles often clustered in a membranous web (MW). During infection, HCV NS5A protein activates PI4KIIIα enzyme, causing massive production and redistribution of phosphatidylinositol 4-phosphate (PI4P) lipid to the repli...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Khan, Irfan, Katikaneni, Divya S., Han, Qingxia, Sanchez-Felipe, Lorena, Hanada, Kentaro, Ambrose, Rebecca L., Mackenzie, Jason M., Konan, Kouacou V.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248901/
https://ncbi.nlm.nih.gov/pubmed/25122779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00970-14
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