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Heterogeneity in Rhesus Macaque Complement Factor H Binding to Meningococcal Factor H Binding Protein (FHbp) Informs Selection of Primates To Assess Immunogenicity of FHbp-Based Vaccines

Neisseria meningitidis causes disease only in humans. An important mechanism underlying this host specificity is the ability of the organism to resist complement by recruiting the complement downregulator factor H (FH) to the bacterial surface. In previous studies, binding of FH to one of the major...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Clin Vaccine Immunol
Päätekijät: Beernink, Peter T., Shaughnessy, Jutamas, Stefek, Heather, Ram, Sanjay, Granoff, Dan M.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Microbiology 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248754/
https://ncbi.nlm.nih.gov/pubmed/25185576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.00517-14
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