Metabolic-Stress-Induced Rearrangement of the 14-3-3ζ Interactome Promotes Autophagy via a ULK1- and AMPK-Regulated 14-3-3ζ Interaction with Phosphorylated Atg9

14-3-3ζ promotes cell survival via dynamic interactions with a vast network of binding partners, many of which are involved in stress regulation. We show here that hypoxia (low glucose and oxygen) triggers a rearrangement of the 14-3-3ζ interactome to favor an interaction with the core autophagy reg...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Main Authors: Weerasekara, Vajira K., Panek, David J., Broadbent, David G., Mortenson, Jeffrey B., Mathis, Andrew D., Logan, Gideon N., Prince, John T., Thomson, David M., Thompson, J. Will, Andersen, Joshua L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2014
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248729/
https://ncbi.nlm.nih.gov/pubmed/25266655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00740-14
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