Assessment of the Potential of CDK2 Inhibitor NU6140 to Influence the Expression of Pluripotency Markers NANOG, OCT4, and SOX2 in 2102Ep and H9 Cells

As cyclin-dependent kinases (CDKs) regulate cell cycle progression and RNA transcription, CDKs are attractive targets for creating cancer cell treatments. In this study we investigated the effects of the small molecular agent NU6140 (inhibits CDK2 and cyclin A interaction) on human embryonic stem (h...

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Publicat a:Int J Cell Biol
Autors principals: Kallas, Ade, Pook, Martin, Trei, Annika, Maimets, Toivo
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248398/
https://ncbi.nlm.nih.gov/pubmed/25477962
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/280638
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