Ligand engaged TCR is triggered by Lck not associated with CD8 coreceptor

The earliest molecular events in T cell recognition have not yet been fully described, and the initial T cell receptor (TCR) triggering mechanism remains a subject of controversy. Here, using TIRF/FRET microscopy, we observe a two-stage interaction between TCR, CD8, and MHCp. There is an early (with...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Casas, Javier, Brzostek, Joanna, Zarnitsyna, Veronika I., Hong, Jin-sung, Wei, Qianru, Hoerter, John A.H., Fu, Guo, Ampudia, Jeanette, Zamoyska, Rose, Zhu, Cheng, Gascoigne, Nicholas R.J.
Format: Artigo
Langue:Inglês
Publié: 2014
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4248239/
https://ncbi.nlm.nih.gov/pubmed/25427562
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms6624
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires