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Hydrocarbon molar water solubility predicts NMDA vs. GABA(A) receptor modulation

BACKGROUND: Many anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABA(A)) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar water solubility of a hydrocarbon could b...

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Detaylı Bibliyografya
Yayımlandı:BMC Pharmacol Toxicol
Asıl Yazarlar: Brosnan, Robert J, Pham, Trung L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247779/
https://ncbi.nlm.nih.gov/pubmed/25410726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-62
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