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Hydrocarbon molar water solubility predicts NMDA vs. GABA(A) receptor modulation
BACKGROUND: Many anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABA(A)) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar water solubility of a hydrocarbon could b...
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| Publicado en: | BMC Pharmacol Toxicol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247779/ https://ncbi.nlm.nih.gov/pubmed/25410726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2050-6511-15-62 |
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