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GABA(A) receptor antagonism increases NMDA receptor inhibition by isoflurane at a minimum alveolar concentration
OBJECTIVE: At the minimum alveolar concentration (MAC), isoflurane potentiates GABA(A) receptor currents and inhibits NMDA receptor currents, and these actions may be important for producing anesthesia. However, isoflurane modulates GABA(A) receptors more potently than NMDA receptors. The objective...
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2011
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3128867/ https://ncbi.nlm.nih.gov/pubmed/21492389 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1467-2995.2011.00605.x |
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