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Sensing the enemy within: how macrophages detect intracellular Gram-negative bacteria

Caspase-11 contributes to host defense against Gram-negative bacterial pathogens by inducing an inflammatory form of programmed cell death in infected cells. Lipopolysaccharides (LPS) have been identified as the microbial agents that stimulate caspase-11 activation; however, the mechanism of LPS det...

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Bibliografske podrobnosti
izdano v:Trends Biochem Sci
Main Authors: Demon, Dieter, Vande Walle, Lieselotte, Lamkanfi, Mohamed
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Trends Journals 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4247376/
https://ncbi.nlm.nih.gov/pubmed/25458607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2014.10.006
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