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Global changes in the RNA binding specificity of HIV-1 Gag regulate virion genesis
The HIV-1 Gag protein orchestrates all steps of virion genesis, including membrane targeting and RNA recruitment into virions. Using crosslinking-immunoprecipitation (CLIP) sequencing, we uncover several dramatic changes in the RNA binding properties of Gag that occur during virion genesis, coincide...
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Publicado no: | Cell |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4247003/ https://ncbi.nlm.nih.gov/pubmed/25416948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.09.057 |
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