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Efficient replication of a paramyxovirus independent of full zippering of the fusion protein six-helix bundle domain

Enveloped viruses such as HIV and members of the paramyxovirus family use metastable, proteinaceous fusion machineries to merge the viral envelope with cellular membranes for infection. A hallmark of the fusogenic glycoproteins of these pathogens is refolding into a thermodynamically highly stable f...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Brindley, Melinda A., Plattet, Philippe, Plemper, Richard Karl
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246953/
https://ncbi.nlm.nih.gov/pubmed/25157143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1403609111
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