Diversity and clonal selection in the human T-cell repertoire

T-cell receptor (TCR) diversity, a prerequisite for immune system recognition of the universe of foreign antigens, is generated in the first two decades of life in the thymus and then persists to an unknown extent through life via homeostatic proliferation of naïve T cells. We have used next-generat...

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Enregistré dans:
Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Qi, Qian, Liu, Yi, Cheng, Yong, Glanville, Jacob, Zhang, David, Lee, Ji-Yeun, Olshen, Richard A., Weyand, Cornelia M., Boyd, Scott D., Goronzy, Jörg J.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2014
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246948/
https://ncbi.nlm.nih.gov/pubmed/25157137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1409155111
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