FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells

The forkhead transcription factor FOXP1 is involved in B-cell development and function and is generally regarded as an oncogene in activated B-cell–like subtype of diffuse large B-cell lymphoma (DLBCL) and mucosa-associated lymphoid tissue lymphoma, lymphomas relying on constitutive nuclear factor κ...

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Detalles Bibliográficos
Publicado en:Blood
Main Authors: van Keimpema, Martine, Grüneberg, Leonie J., Mokry, Michal, van Boxtel, Ruben, Koster, Jan, Coffer, Paul J., Pals, Steven T., Spaargaren, Marcel
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2014
Assuntos:
Lymphoid Neoplasia
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246697/
https://ncbi.nlm.nih.gov/pubmed/25267198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-01-553412
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