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Biological redundancy of endogenous GPCR ligands in the gut and the potential for endogenous functional selectivity

This review focuses on the existence and function of multiple endogenous agonists of the somatostatin and opioid receptors with an emphasis on their expression in the gastrointestinal tract. These agonists generally arise from the proteolytic cleavage of prepropeptides during peptide maturation or f...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Thompson, Georgina L., Canals, Meritxell, Poole, Daniel P.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246669/
https://ncbi.nlm.nih.gov/pubmed/25506328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2014.00262
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