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Opportunities for Functional Selectivity in GPCR Antibodies

Monoclonal antibodies (mAbs) have been used for decades as tools to probe the biology and pharmacology of receptors in cells and tissues. They are also increasingly being developed for clinical purposes against a broad range of targets, albeit to a lesser extent for G protein-coupled receptors (GPCR...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Webb, D. R., Handel, Tracy M., Kretz-Rommel, Anke, Stevens, Raymond C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729224/
https://ncbi.nlm.nih.gov/pubmed/22975405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2012.08.021
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