Folliculin regulates cell–cell adhesion, AMPK, and mTORC1 in a cell‐type‐specific manner in lung‐derived cells

Germline loss‐of‐function BHD mutations cause cystic lung disease and hereditary pneumothorax, yet little is known about the impact of BHD mutations in the lung. Folliculin (FLCN), the product of the Birt–Hogg–Dube (BHD) gene, has been linked to altered cell–cell adhesion and to the AMPK and mTORC1...

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Dades bibliogràfiques
Publicat a:Physiol Rep
Autors principals: Khabibullin, Damir, Medvetz, Douglas A., Pinilla, Miguel, Hariharan, Venkatesh, Li, Chenggang, Hergrueter, Anja, Laucho Contreras, Maria, Zhang, Erik, Parkhitko, Andrey, Yu, Jane J., Owen, Caroline A., Huang, Hayden, Baron, Rebecca M., Henske, Elizabeth P.
Format: Artigo
Idioma:Inglês
Publicat: Wiley Periodicals, Inc. 2014
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246594/
https://ncbi.nlm.nih.gov/pubmed/25121506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14814/phy2.12107
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