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Lysophosphatidic acid and its receptors LPA(1) and LPA(3) mediate paclitaxel-induced neuropathic pain in mice

BACKGROUND: Paclitaxel, which is widely used for the treatment of solid tumors, causes neuropathic pain via poorly understood mechanisms. Previously, we have demonstrated that lysophosphatidic acid (LPA) and its receptors (LPA(1) and LPA(3)) are required for the initiation of peripheral nerve injury...

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Vydáno v:Mol Pain
Hlavní autoři: Uchida, Hitoshi, Nagai, Jun, Ueda, Hiroshi
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246549/
https://ncbi.nlm.nih.gov/pubmed/25411045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-71
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