Autotaxin, a synthetic enzyme of lysophosphatidic acid (LPA), mediates the induction of nerve-injured neuropathic pain

Recently, we reported that lysophosphatidic acid (LPA) induces long-lasting mechanical allodynia and thermal hyperalgesia as well as demyelination and upregulation of pain-related proteins through one of its cognate receptors, LPA(1). In addition, mice lacking the LPA(1 )receptor gene (lpa(1)(-/- )m...

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Autors principals: Inoue, Makoto, Ma, Lin, Aoki, Junken, Chun, Jerold, Ueda, Hiroshi
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2008
Matèries:
Short Report
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2277392/
https://ncbi.nlm.nih.gov/pubmed/18261210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-4-6
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