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Lysophosphatidic acid and its receptors LPA(1) and LPA(3) mediate paclitaxel-induced neuropathic pain in mice

BACKGROUND: Paclitaxel, which is widely used for the treatment of solid tumors, causes neuropathic pain via poorly understood mechanisms. Previously, we have demonstrated that lysophosphatidic acid (LPA) and its receptors (LPA(1) and LPA(3)) are required for the initiation of peripheral nerve injury...

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Publicado en:Mol Pain
Autores principales: Uchida, Hitoshi, Nagai, Jun, Ueda, Hiroshi
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246549/
https://ncbi.nlm.nih.gov/pubmed/25411045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-10-71
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