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Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites
BACKGROUND: Emerging studies demonstrate that single nucleotide polymorphisms (SNPs) resided in the microRNA recognition element seed sites (MRESSs) in 3′UTR of mRNAs are putative biomarkers for human diseases and cancers. However, exhaustively experimental validation for the causality of MRESS SNPs...
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| Publicado no: | BMC Genomics |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246476/ https://ncbi.nlm.nih.gov/pubmed/25106527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-669 |
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