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Genome-wide association study combined with biological context can reveal more disease-related SNPs altering microRNA target seed sites
BACKGROUND: Emerging studies demonstrate that single nucleotide polymorphisms (SNPs) resided in the microRNA recognition element seed sites (MRESSs) in 3′UTR of mRNAs are putative biomarkers for human diseases and cancers. However, exhaustively experimental validation for the causality of MRESS SNPs...
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| Pubblicato in: | BMC Genomics |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246476/ https://ncbi.nlm.nih.gov/pubmed/25106527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-669 |
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