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EGR2 is critical for peripheral naïve T-cell differentiation and the T-cell response to influenza
Early growth response 2 (EGR2) transcription factor negatively regulates T-cell activation, in contrast to the positive regulation of this process by EGR1. Here, we unexpectedly found that EGR2 promotes peripheral naïve T-cell differentiation, with delayed T-cell receptor-induced proliferation in na...
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| Опубликовано в: : | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246296/ https://ncbi.nlm.nih.gov/pubmed/25368162 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1417215111 |
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