RNase L Attenuates Mitogen-stimulated Gene Expression via Transcriptional and Post-transcriptional Mechanisms to Limit the Proliferative Response

The cellular response to mitogens is tightly regulated via transcriptional and post-transcriptional mechanisms to rapidly induce genes that promote proliferation and efficiently attenuate their expression to prevent malignant growth. RNase L is an endoribonuclease that mediates diverse antiprolifera...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Brennan-Laun, Sarah E., Li, Xiao-Ling, Ezelle, Heather J., Venkataraman, Thiagarajan, Blackshear, Perry J., Wilson, Gerald M., Hassel, Bret A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Gene Regulation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246114/
https://ncbi.nlm.nih.gov/pubmed/25301952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.589556
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