Coordinated Expression of Tristetraprolin Post-Transcriptionally Attenuates Mitogenic Induction of the Oncogenic Ser/Thr Kinase Pim-1

The serine/threonine kinase Pim-1 directs selected signaling events that promote cell growth and survival and is overexpressed in diverse human cancers. Pim-1 expression is tightly controlled through multiple mechanisms, including regulation of mRNA turnover. In several cultured cell models, mitogen...

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Detalhes bibliográficos
Main Authors: Mahat, Dig B., Brennan-Laun, Sarah E., Fialcowitz-White, Elizabeth J., Kishor, Aparna, Ross, Christina R., Pozharskaya, Tatyana, Rawn, J. David, Blackshear, Perry J., Hassel, Bret A., Wilson, Gerald M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3297641/
https://ncbi.nlm.nih.gov/pubmed/22413002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033194
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