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Regulation of Human RNase-L by the miR-29 Family Reveals a Novel Oncogenic Role in Chronic Myelogenous Leukemia
The endoribonuclease RNase-L is the terminal component of an interferon-regulated RNA decay pathway known as the 2′-5′-oligoadenylate (2–5A) system, whose established functions include antimicrobial and tumor suppressive activities. RNase-L activity requires binding of the small molecule 2–5A, leadi...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Mary Ann Liebert, Inc.
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3539258/ https://ncbi.nlm.nih.gov/pubmed/23113544 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/jir.2012.0062 |
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