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G Protein Signaling Modulator-3 Inhibits the Inflammasome Activity of NLRP3
Inflammasomes are multi-protein complexes that regulate maturation of the interleukin 1β-related cytokines IL-1β and IL-18 through activation of the cysteine proteinase caspase-1. NOD-like receptor family, pyrin domain containing 3 (NLRP3) protein is a key component of inflammasomes that assemble in...
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| Veröffentlicht in: | J Biol Chem |
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| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4246083/ https://ncbi.nlm.nih.gov/pubmed/25271165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.578393 |
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