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Highly Conserved Residues in the Helical Domain of Dengue Virus Type 1 Precursor Membrane Protein Are Involved in Assembly, Precursor Membrane (prM) Protein Cleavage, and Entry

The envelope and precursor membrane (prM) proteins of dengue virus (DENV) are present on the surface of immature virions. During maturation, prM protein is cleaved by furin protease into pr peptide and membrane (M) protein. Although previous studies mainly focusing on the pr region have identified s...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Hsieh, Szu-Chia, Wu, Yi-Chieh, Zou, Gang, Nerurkar, Vivek R., Shi, Pei-Yong, Wang, Wei-Kung
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246076/
https://ncbi.nlm.nih.gov/pubmed/25326389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.610428
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