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The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry

The role of the α-helical domain (MH) of dengue virus (DENV) precursor membrane protein in replication was investigated by site-directed mutagenesis. Proline substitutions of three residues (120, 123 and 127) at the C-terminus, but not those at the N-terminus of MH domain, reduced the virus-like par...

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Dettagli Bibliografici
Autori principali: Hsieh, Szu-Chia, Zou, Gang, Tsai, Wen-Yang, Qing, Min, Chang, Gwong-Jen, Shi, Pei-Yong, Wang, Wei-Kung
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3100346/
https://ncbi.nlm.nih.gov/pubmed/21129763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.11.006
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