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The C-terminal helical domain of dengue virus precursor membrane protein is involved in virus assembly and entry
The role of the α-helical domain (MH) of dengue virus (DENV) precursor membrane protein in replication was investigated by site-directed mutagenesis. Proline substitutions of three residues (120, 123 and 127) at the C-terminus, but not those at the N-terminus of MH domain, reduced the virus-like par...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100346/ https://ncbi.nlm.nih.gov/pubmed/21129763 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2010.11.006 |
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