Radio-sensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector

A tumor-selective non-lytic retroviral replicating vector (RRV), Toca 511, and an extended-release formulation of 5-fluorocytosine (5-FC), Toca FC, are currently being evaluated in clinical trials in patients with recurrent high-grade glioma (NCT01156584, NCT01470794, NCT01985256). Tumor-selective p...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Cancer Gene Ther
मुख्य लेखकों: Takahashi, Masamichi, Valdes, Gilmer, Hiraoka, Kei, Inagaki, Akihito, Kamijima, Shuichi, Micewicz, Ewa, Gruber, Harry E., Robbins, Joan M., Jolly, Douglas J., McBride, William H., Iwamoto, Keisuke S., Kasahara, Noriyuki
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2014
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4246057/
https://ncbi.nlm.nih.gov/pubmed/25301172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2014.38
टैग : टैग जोड़ें
कोई टैग नहीं, इस रिकॉर्ड को टैग करने वाले पहले व्यक्ति बनें!

समान संसाधन