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Oxidative DNA damage is instrumental in hyperreplication stress-induced inviability of Escherichia coli

In Escherichia coli, an increase in the ATP bound form of the DnaA initiator protein results in hyperinitiation and inviability. Here, we show that such replication stress is tolerated during anaerobic growth. In hyperinitiating cells, a shift from anaerobic to aerobic growth resulted in appearance...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Charbon, Godefroid, Bjørn, Louise, Mendoza-Chamizo, Belén, Frimodt-Møller, Jakob, Løbner-Olesen, Anders
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4245963/
https://ncbi.nlm.nih.gov/pubmed/25389264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku1149
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